Sanofi confirms suspected safety issue with dengue vaccine

Sanofi confirms suspected safety issue with dengue vaccine

The vaccination programme in schools across the Philippines has been suspended after evidence showed it could make symptoms more severe in children who hadn't previously had the illness.

Pharmaceutical giant Sanofi on Monday said there have been no reported deaths in the Philippines related to the P3.4 billion dengue vaccination program that has been suspended by the Philippine government.

Most of the study participants who fell ill after receiving the vaccine had cases in the milder two of four levels of severity: Dengue Hemorrhagic Fever 1, where a tourniquet test is positive and a patient easily bruises and DHF 2, where the patient's nose and gums could bleed.

Senator Joel Villanueva sought to revive a congressional probe on the dengue vaccination programme to determine whether some health officials should be held responsible "for haphazardly allowing the vaccine to be administered without extensive due diligence on the effects and without waiting for the results of a comprehensive clinical trial".

Over 700,000 Filipino children were vaccinated with a dose of Dengvaxia last year in line with the recommendation of the World Health Organization for mass vaccination in highly endemic countries.

In its alert, Sanofi said further clinical studies had revealed that, in those who had previously had dengue, the vaccine could prevent repeat infection.

Khristine Estrada-Cabanayan, a Sanofi spokeswoman in the Philippines, said the company is working closely with the Department of Health and will release a statement to address concerns regarding the vaccine.

Inter goleó y es líder en solitario de la Serie A
Sobre el final, Perisic completó su "hat-trick" con un zurdazo bajo y coronó la espectacular goleada del nuevo líder. Y hoy juegan también: Benevento 2-Milan 2, Bologna 1-Cagliari 1, Fiorentina 3-Sassuolo 0 y Sampdoria-Lazio (16.30).

Three children given Sanofi's dengue vaccine in Central Luzon have allegedly died, the Volunteers Against Crime and Corruption claimed Monday.

The office of the Philippine president vowed to hold accountable those responsible for the dengue immunisation programme, which said it placed lives at risk.

Dr Ng Su Peing, Sanofi's global medical head, said nine in 10 Filipinos will be exposed to the dengue virus by the time they reach adolescence.

"As far as we know, as far as we are made aware, there are no reported deaths that are related to dengue vaccination", Ruby Dizon, medical director at Sanofi Pasteur, told reporters.

But, the vaccine does the opposite of what it's supposed to do, and actually increases the risk of contracting more severe dengue for those who have never been infected before.

Justice Secretary Vitaliano Aguirre said he will order the National Bureau of Investigation to determine if Sanofi Pasteur, which manufactures the vaccine, gave the Department of Health "proper warning" on the vaccine's possible risks.